| Date | Location | Result | |
| 11/13/2010 | Cleveland, OH | Case Western Reserve 28, Carnegie Mellon 0 | Box score |
| 11/13/2010 | Chicago, Ill. | Chicago 13, Washington 10 | Box score |
| 11/06/2010 | Cleveland, OH | Washington 14, Case Western Reserve 13 | Box score |
| 11/06/2010 | Pittsburgh, Pa. | Chicago 61, Carnegie Mellon 22 | Box score |
| 10/30/2010 | St. Louis, Mo. | Washington 20, Carnegie Mellon 13 | Box score |
| 10/30/2010 | Chicago, Ill. | Chicago 24, Case Western Reserve 20 | Box score |
| 10/23/2010 | Gambier, Ohio | Chicago 35, Kenyon 14 | Box score |
| 10/23/2010 | St. Louis, Mo. | Washington 21, Oberlin College 7 | Box score |
| 10/23/2010 | Cleveland, OH | Case Western Reserve 28, College of Wooster 14 | Box score |
| 10/23/2010 | Pittsburgh, Pa. | Wittenberg 27, Carnegie Mellon 21 | Box score |
| 10/16/2010 | Wooster, Ohio | Washington 14, College of Wooster 13 | Box score |
| 10/16/2010 | Hiram, OH | Case Western Reserve 41, Hiram 0 | Box score |
| 10/09/2010 | St. Louis, Mo. | Washington 24, Wabash 20 | Box score |
| 10/09/2010 | Chicago, Ill. | Chicago 36, Denison 7 | Box score |
| 10/09/2010 | Delaware, Ohio, USA | Carnegie Mellon 35, Ohio Wesleyan 23 | Box score |
| 10/09/2010 | Oberlin, Ohio | Case Western Reserve 48, Oberlin College 36 | Box score |
| 10/02/2010 | Cleveland, OH | Case Western Reserve 24, ALLEGHENY 23 | Box score |
| 10/02/2010 | Pittsburgh, Pa. | Carnegie Mellon 62, Hiram 31 | Box score |
| 10/02/2010 | Chicago, Ill. | Chicago 30, Ohio Wesleyan 6 | Box score |
| 09/25/2010 | St. Louis, Mo. | Washington 36, Westminster 6 | Box score |
| 09/25/2010 | Cleveland, OH | Case Western Reserve 37, Denison 7 | Box score |
| 09/25/2010 | Crawfordsville, IN | Wabash 31, Chicago 14 | Box score |
| 09/25/2010 | Pittsburgh, Pa. | Carnegie Mellon 17, Kenyon 10 | Box score |
| 09/18/2010 | Elmhurst, Ill. | Elmhurst 31, Chicago 20 | Box score |
| 09/18/2010 | Springfield, Ohio | Wittenberg 37, Washington 7 | Box score |
| 09/18/2010 | Pittsburgh, Pa. | Hobart 35, Carnegie Mellon 21 | Box score |
| 09/11/2010 | Rochester, NY | Case Western Reserve 14, Rochester 10 | Box score |
| 09/11/2010 | Memphis, Tenn. | Rhodes Lynx 14, Washington 10 | Box score |
| 09/11/2010 | Chicago, Ill. | Chicago 56, Concordia Chicago 24 | Box score |
| 09/11/2010 | Meadville, Pa. | ALLEGHENY 34, Carnegie Mellon 27 | Box score |
| 09/04/2010 | Beloit, Wis. | Chicago 28, Beloit College 25 | Box score |
| 09/04/2010 | St. Louis, Mo. | Washington 34, Knox College 3 | Box score |
| 09/04/2010 | Cleveland, OH | Case Western Reserve 30, John Carroll 13 | Box score |
| 09/04/2010 | Grove City, Pa. | Carnegie Mellon 28, Grove City 21 | Box score |